Olivia Hallisey

Temperature-Independent, Portable, and Rapid Field Detection of Ebola via a Silk-Derived Lateral-Flow System

Olivia Hallisey, USA Grand prize winner, 16-18

Current Ebola detection methods are complex, expensive, require unbroken refrigeration from manufacture to use and up to 12 hours from testing to confirmed diagnosis. This research creates a “stable and stored at room temperature” temperature-independent Ebola Assay Card (EAC), which utilizes the stabilizing properties of silk fibroin to "break the cold chain" and allow for water-activated detection of Ebola antigens, with detection limits that are analogous to current sandwich ELISA techniques. The EAC provides rapid, inexpensive, accurate detection of Ebola viral antigens based on color change within 30 minutes in individuals prior to their becoming symptomatic and infectious.

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